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Category Archives: BRCA 1 or BRCA2 genetic mutation
For many women with localized breast cancer, a lumpectomy followed by breast radiation therapy may be the most effective treatment, with survival rates equal to a mastectomy. But if the cancer comes back, can women have additional lumpectomies?
Women should not have a second lumpectomy in the same breast if they were previously
Mehra Golshan, MD, FACS, director of Breast Surgical Services with the Susan F. Smith Center for Women’s Cancers at Dana-Farber, meets with patients to customize breast surgery approaches.
treated with a lumpectomy and radiation, says Mehra Golshan, MD, FACS, director of Breast Surgical Services at the Susan F. Smith Center …
There’s a broad range of news and information about breast cancer online. That creates wonderful opportunities to learn about prevention, treatment, cures and recurrence. But it also means you may run into confusing misinformation and oversimplifications.
Here are some popular misconceptions:
Most breast cancer is hereditary. While it’s true that a woman’s risk factor for developing breast cancer doubles if a first-degree relative has the disease, this statistic doesn’t tell the whole story.
In the vast majority of cases, breast cancer is not caused by an inherited gene defect (or mutation).
Only 5 to 10 percent of breast cancer is associated with a gene …
by Christine Hensel Triantos
Beyond BRCA1 and BRCA2:
Other Gene Mutations Linked to Cancer Risk
Many women with a family history of breast or ovarian cancer choose genetic testing to find out if they have inherited BRCA1 or BRCA2 gene mutations, which could put them and their family members at a higher risk for these cancers. Now a panel test – known as BROCA – is available for women to learn if they have other gene mutations linked to breast and ovarian cancer.
The panel includes mutations in about 25 genes associated with an increased risk for breast or ovarian cancer, and that number …
Shoshana Rosenberg, ScD, MPH
Young women with breast cancer often overestimate the odds that cancer will occur in their other, healthy breast, and decide to have the healthy breast surgically removed, a survey conducted by Dana-Farber Cancer Institute investigators indicates. The survey also shows that many patients opt for the procedure – known as a contralateral prophylactic mastectomy, or CPM – despite knowing it will be unlikely to improve their chance of survival.
The study, published in the Sept. 17 issue of the Annals of Internal Medicine, shows a certain disconnect between what many patients know on an abstract, intellectual level – …
Angelina Jolie decision to share her story about being tested for the breast cancer gene and undergoing a double mastectomy is major and will help so many men and women. It is incredible that as such a public figure, she was able to keep her story private until she wanted to share it with the world.
Shared it now is!
Since writing her story on the Op-Ed page of the New York Times, every newspaper, news cast and social media is abuzz with her story. Her honesty and truthfulness will help many make a very tough decision.
Here is my story about how …
With Breast Cancer Awareness Month fast approaching, I checked out the web for some misconceptions about breast cancer. It turns out there are many! Here are the top 10 from fellow breast cancer survivor, Sheryl Kraft, which can also be found here:
1. Breast pain is a symptom of breast cancer. That’s rarely the case; breast cancer, especially early breast cancer, usually does not cause pain and may exhibit no noticeable symptoms. Most aches, pains or tenderness can be attributed to things like fibrocystic breast changes and the rise and fall of hormones, or a benign fluid-filled sac (a cyst), which …
Many of us travel a similar road once diagnosed with breast cancer…surgery, chemo, radiation and all that goes with it. Eventually we reach the end of active treatment. For some of us the road has a different course… more aggressive treatment, harder choices to make and active treatment that continues indefinitely.
For women diagnosed with rare and very aggressive cancers, women who test positive for the BRCA1 or BRCA2 genetic mutation, women diagnosed with breast cancer while pregnant and women whose first diagnosis is metastatic breast cancer, the road is long and sometimes unending.
Women diagnosed with Paget’s Disease of the Nipple, …