Tag Archives: genetic alterations

Breast cancer’s many drivers

New genetic alterations discovered through US-Mexico sequence-analysis collaboration
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes that drive breast cancer is revealing new complexity in the leading cause of cancer death in women worldwide.
In one of the largest breast cancer sequencing efforts to date, scientists from the Broad Institute, Dana-Farber Cancer Institute, the National Institute of Genomic Medicine in Mexico City, and Beth Israel Deaconess Medical Center have discovered surprising alterations in genes that were …